Co-Crystals in Pharmaceutical Sciences

Co-Crystals in Pharmaceutical Sciences: Design in Applications is a comprehensive overview of the field of pharmaceutical co-crystals. It addresses fundamental principles, practical considerations, and the regulatory landscape. The book begins by introducing the concept’s broad scope and potential impact on drug development. The book then delves into design principles and molecular interactions, emphasizing the structural characteristics that influence cocrystals. Unique chapters explore herbal and drug-drug cocrystals, detailing experimental techniques, validation, and process optimization. By addressing these aspects, this book can bridge the gap between laboratory research, ensuring cocrystals become a viable tool in drug development.

Chapters on pharmaceutical applications explore how co-crystal roles enhance suitability, stability, and therapeutic challenges, supported by real-world examples. Computational screening and characterization techniques that offer insights into evaluating cocrystals are included in the designated chapters. In addition, sections also discuss the concepts of herbal and commercial perspectives of pharmaceutical cocrystals. The section further explains how cocrystals can improve active pharmaceutical ingredients solubility, mechanical properties, and stability as explained with the recent research. Finally, a detailed regulatory perspective of pharmaceutical cocrystal has been discussed in detail.